This repository houses the analysis codes from the Bayesian preclinical tutorial paper led by the DIA/ASA-BIOP Nonclinical Bayesian Working Group members.

A 3D printable design for Bruker preclinical MRI using the 2x2 mouse or rat surface array coil for any abdominal imaging instead of brain.

Deep learning pipeline for automated semantic segmentation and endotheliosis quantification in glomeruli histology images using transfer learning from mitochondria electron microscopy images

Glioblastoma (GBM) remains lethal despite multimodal therapy, with median survival under 15 months. Immunotherapy has failed in over 100 clinical trials due to three fundamental barriers: inadequate immune priming in "cold" tumors, blood–brain barrier (BBB) exclusion of therapeutics, and profound local immunosuppression.

Reproduces the results of "Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes"

pose-estimation for pre-clinical drug validation

Miscellaneous 3D printing designs related to preclinical imaging.

A modification on a published 3D printing design for mouse or rat brain MRI imaging.

A 3D printable design to scan on the Inveon PET/CT with 4 mice simultaneously, dynamically.