This repository contains source code for the single-cell transcriptomics analysis of mouse astrocyte subtypes characterized by calcium responses to alcohol exposure [1].
Youtao Lu ([email protected])
Creative Commons Attribution License 4.0 (CC BY)
[1] Hyun-Bum Kim, Youtao Lu, Seonkyung C Oh, Jacqueline Morris, Kevin Miyashiro, Junhyong Kim, James Eberwine and Jai-Yoon Sul. "Astrocyte ethanol exposure reveals persistent and defined calcium response subtypes and associated gene signatures" (Journal of Biological Chemistry, 298 (8), 2022)
In the original publication [1], Fig. 4A, the "Mitochondria" heatmap (column 2) and the "Calcium" heatmap (column 3) got mistakenly swapped. It has been corrected in the Juypter Notebook 04.pathway.ipynb (cell 29 and 30). Since Fig. 4A only serves visual introduction to section S- and T-types differentially express inflammatory factors and regulators of intracellular calcium, mitochondrial function, and the epigenome, and all Fig. 4 related discussion and conclusion are based on Fig. 4B (the barcharts) and Table genesets.csv, we confirm that this mistake does not affect any discussion or conclusion. However, we apologize for the mistake.