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Fluconazole plus flucytosine vs. fluconazole alone for cryptococcal antigen-positive patients identified through screening: A phase III randomised controlled trial

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EFFECT Edc

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The EFFECT Trial

Fluconazole plus flucytosine vs. fluconazole alone for cryptococcal antigen-positive patients identified through screening: A phase III randomised controlled trial

(EFFECT - Efficacy of Flucytosine and Fluconazole as Early Cryptococcal Treatment)

https://www.isrctn.com/ISRCTN30579828

Homepage: https://github.com/effect-trial/

Documentation: https://effect-edc.readthedocs.io/en/latest/

Made with Django

Installation

To setup and run a test server locally

You'll need mysql. Create the database

mysql -Bse 'create database effect character set utf8;'

Clone the main repo and checkout main

mkdir ~/projects
cd projects
https://github.com/effect-trial/effect-edc.git
cd ~/projects/effect-edc
git checkout main

Create a venv with uv

uv venv
source .venv/bin/activate
uv sync --no-sources --upgrade

Copy the test environment file

mkdir ~/.clinicedc/effect_edc
cd ~/projects/effect-edc
cp .env.tests ~/.clinicedc/effect_edc/.env

Edit the environment file (.env) to include your mysql password in the DATABASE_URL.

# look for and update this line
DATABASE_URL=mysql://user:[email protected]:3306/effect

Continue with the installation. FOr this example we setup up a test server (DEBUG=True)

cd ~/projects/effect-edc
python manage.py migrate --settings=effect_edc.settings.debug
python manage.py import_randomization_list
python manage.py import_holidays

Create a user and start up runserver

cd ~/projects/effect-edc
git checkout main
python manage.py createsuperuser
python manage.py runserver

Login:

http://localhost:8000

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Fluconazole plus flucytosine vs. fluconazole alone for cryptococcal antigen-positive patients identified through screening: A phase III randomised controlled trial

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