This repository contains reference VG estimates from population level reference datasets using our ANEVA-h framework. The value of VG can be used for performing outlier testing for allele-specific expression (ASE) Data using ANEVA-DOT.
Each file is an excel file with the following:
- Each row corresponds to a gene ID (idenitifed by ENSEMBL ID)
- For GTEx, each column is a tissue (abbreviated) with corresponding values being the VG of the gene (lower bound, VG, upperbound) from a 95% parametric confidence interval.
- For MAGE, each column in an ancestry group with corresponding values being the VG of the gene (lower bound, VG, upperbound) from a parametric bootrap.
gtex_vg.xlsx: VG computed from 15,000+ RNA-seq samples spanning 49 GTEx (v8) tissues with over 25 samples per tissue. VGs are computed per tissue using ASE data from here and with tissue abbreviations consistent with our previous efforts.
mage_vg.xlsx: VG computed from 701 LCL cell-lines spanning 25 population groups in MAGE with ASE data derived from here. VGs are computed per tissue with abbreviations consistent with our previous efforts.