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@NIGMS

National Institute of General Medical Sciences

Increasing our understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention.

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  1. NIGMS-Sandbox NIGMS-Sandbox Public

    Collection of cloud-based biomedical data science learning modules funded by the National Institute of General Medical Sciences at the NIH

    Shell 77 23

  2. DNA-Methylation-Sequencing-Analysis-with-WGBS DNA-Methylation-Sequencing-Analysis-with-WGBS Public

    In this module, you will learn how to download raw sequence data, calculate differentially methylated regions, and run a canonical methyl-seq pipeline in Nextflow

    Jupyter Notebook 15 4

  3. Biomedical-Imaging-Analysis-using-AI-ML-Approaches Biomedical-Imaging-Analysis-using-AI-ML-Approaches Public

    Machine Learning module for cloud-based analyses developed as part of the NIGMS Sandbox Project

    Jupyter Notebook 11 6

  4. Integrating-Multi-Omics-Datasets Integrating-Multi-Omics-Datasets Public

    Multi-omics module that includes RNAseq, Epigenetics, and integrated multi-omics analyses developed as part of the NIGMS Sandbox project

    HTML 9 2

  5. ATAC-Seq-and-Single-Cell-ATAC-Seq-Analysis ATAC-Seq-and-Single-Cell-ATAC-Seq-Analysis Public

    ATAC-seq and scATAC-seq module developed by the University of Nebraska Medical Center

    Jupyter Notebook 9 6

  6. Introduction-to-Data-Science-for-Biology Introduction-to-Data-Science-for-Biology Public

    Python-based machine learning and data science module from SFSU developed for the NIGMS Sandbox project

    Jupyter Notebook 8 7

Repositories

Showing 10 of 33 repositories
  • Structural-Biology-and-Drug-Discovery Public

    This repository provides a comprehensive module on structural biology and drug discovery, covering protein structure, docking, and drug design. It runs on Google Cloud Platform using Jupyter notebooks and includes tools like PyMOL and AutoDock.

    NIGMS/Structural-Biology-and-Drug-Discovery’s past year of commit activity
    HTML 0 CC0-1.0 0 0 0 Updated Aug 21, 2025
  • Consensus-Pathway-Analysis-in-the-Cloud Public

    Consensus pathway analysis module developed by the University of Nevada at Reno

    NIGMS/Consensus-Pathway-Analysis-in-the-Cloud’s past year of commit activity
    HTML 2 5 0 1 Updated Jun 9, 2025
  • Transcriptome-Assembly-Refinement-and-Applications Public

    In this module, you will learn how to use a Nextflow pipeline to assemble and annotate a novel transcriptome using RNA-seq data

    NIGMS/Transcriptome-Assembly-Refinement-and-Applications’s past year of commit activity
    Jupyter Notebook 0 4 0 0 Updated Jun 9, 2025
  • RNA-Seq-Differential-Expression-Analysis Public

    RNAseq workflow run using BASH, Nextflow, and Snakemake on AWS and GCP, developed as part of the NIH NIGMS Sandbox

    NIGMS/RNA-Seq-Differential-Expression-Analysis’s past year of commit activity
    Jupyter Notebook 4 2 0 0 Updated Jun 9, 2025
  • Protein-Protein-Interactions-using-ML Public

    In this module, you will harness novel machine learning techniques to investigate how proteins behave. A special focus will be given to data preprocessing, model training, and evaluation techniques to uncover complex biological relationships

    NIGMS/Protein-Protein-Interactions-using-ML’s past year of commit activity
    Jupyter Notebook 0 CC0-1.0 0 0 0 Updated Jun 9, 2025
  • Foundations-of-Python-for-Data-Science Public

    This repository offers an introductory Python module for bioinformatics, emphasizing practical coding techniques for biological scientists. It covers Python basics, data handling with NumPy and Pandas, and cloud computing on Azure.

    NIGMS/Foundations-of-Python-for-Data-Science’s past year of commit activity
    Jupyter Notebook 0 CC0-1.0 1 0 0 Updated Jun 9, 2025
  • Comparative-Microbial-Genomics Public

    In this module, you will learn how sequencing data is generated and go through a detailed guide on assembling, assessing, and annotating a bacterial genome. You will then automate the workflow and perform a large-scale comparative genomic analysis.

    NIGMS/Comparative-Microbial-Genomics’s past year of commit activity
    Jupyter Notebook 1 CC0-1.0 1 0 1 Updated Jun 9, 2025
  • RNA-Methylation-with-MeRIP-seq Public

    The MeRIP-seq data analysis tutorial is structured into four submodules, designed to comprehensively guide users through the complete workflow for RNA methylation analysis

    NIGMS/RNA-Methylation-with-MeRIP-seq’s past year of commit activity
    HTML 0 CC0-1.0 0 0 0 Updated Jun 6, 2025
  • Intro-to-Pangenomics Public

    This repository provides a comprehensive module on graphical pangenomics, guiding users through building, indexing, mapping, and visualizing pangenome graphs. The module runs on Google Cloud Platform using Jupyter notebooks and includes tools like PGGB, vg, BLAST, and Bandage.

    NIGMS/Intro-to-Pangenomics’s past year of commit activity
    HTML 0 0 0 0 Updated Jun 6, 2025
  • Proteome-Quantification Public

    Secondary analysis of Proteomics data in R, developed by the University of Arkansas for Medical Sciences for the NIH NIGMS Sandbox project.

    NIGMS/Proteome-Quantification’s past year of commit activity
    Jupyter Notebook 1 5 0 0 Updated Jun 6, 2025

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