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RAS, estrogen, calcium, and bone

This code is for the manuscript Stadt and Layton, "A physiology-based mathematical model of the renin-angiotensin system, bone remodeling, and calcium homeostasis: Effects of estrogen and renin-angiotensin system inhibitors", submitted The manuscript is under review.

Key files

driver_ANGandPTHinf.m run this script to conduct the PTH and Ang II infusion experiments

driver_multi_RASi.m run this script to run simulations of age-related estrogen decline with and without RAS inhibitors of varying efficacy

driver_vary_age.m run this script to run simulations of age-related estrogen decline with RASi starting at varied ages

driverSS.m run this script to compute the model steady state

./simbiology version this directory contains a Simbiology version of the model and scripts for running Sobol sensitivity analysis

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Code for the estrogen, RAS, bone, and calcium model

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