diff --git a/README.md b/README.md
index 9e01dc1c..3a1441ab 100644
--- a/README.md
+++ b/README.md
@@ -225,7 +225,7 @@ In order to launch the debugger using the correct Ruby version, rdbg allows conf
 
 ```jsonc
 // Default value is "none" for not using a version manager to activate the environment
-// Available managers are shadowenv, chruby, asdf, rbenv and rvm
+// Available managers are shadowenv, chruby, asdf, rbenv, mise and rvm
 
 {
   // User settings
diff --git a/package.json b/package.json
index ff182edd..8837c2c7 100644
--- a/package.json
+++ b/package.json
@@ -231,6 +231,7 @@
 						"asdf",
 						"rbenv",
 						"rvm",
+						"mise",
 						"none"
 					],
 					"default": "none"
diff --git a/src/extension.ts b/src/extension.ts
index 15cf6748..a361f0f2 100644
--- a/src/extension.ts
+++ b/src/extension.ts
@@ -32,6 +32,7 @@ enum VersionManager {
 	Rbenv = "rbenv",
 	Rvm = "rvm",
 	Shadowenv = "shadowenv",
+	Mise = "mise",
 	None = "none",
 }
 
@@ -379,6 +380,10 @@ class RdbgAdapterDescriptorFactory implements DebugAdapterDescriptorFactory, Ver
 						?.activate();
 					await this.sleepMs(500);
 					break;
+				case VersionManager.Mise:
+					command = this.makeShellCommand('mise exec ruby -- ruby' + rubyEnvCommand);
+					await this.injectRubyEnvironment(command, cwd);
+					break;
 				default:
 					return;
 			}