-
Notifications
You must be signed in to change notification settings - Fork 0
/
Copy pathindex.html
328 lines (308 loc) · 18.2 KB
/
index.html
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
<!DOCTYPE html>
<html lang="en">
<head>
<title>Home | Mesirov Lab</title>
<meta charset="utf-8">
<meta name="viewport" content="width=device-width, initial-scale=1">
<link rel="stylesheet" href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css">
<script src="https://ajax.googleapis.com/ajax/libs/jquery/3.3.1/jquery.min.js"></script>
<script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.4.0/js/bootstrap.min.js"></script>
<link rel="stylesheet" href="https://use.fontawesome.com/releases/v5.5.0/css/all.css" integrity="sha384-B4dIYHKNBt8Bc12p+WXckhzcICo0wtJAoU8YZTY5qE0Id1GSseTk6S+L3BlXeVIU" crossorigin="anonymous">
<!-- IE6-10 -->
<link rel="shortcut icon" href="img/meslab.ico">
<!-- Everybody else -->
<link rel="icon" href="img/meslab.ico">
<link type="text/css" rel="stylesheet" href="css/styles.css">
<style >
body {
padding-top: 0px;
}
#banner {
margin:0 auto;
padding: 0 auto;
}
.navbar {
background: transparent;
border: none;
}
.navbar-nav li a {
color:white;
}
.dropdown.open a {
background: transparent !important;
}
.navbar-fixed-top.scrolled {
background-color: white;
border-bottom: 1px solid black;
transition: background-color 200ms linear;
}
.navbar-fixed-top.scrolled .iconbar {
border: 1px solid black
}
.navbar-fixed-top.scrolled li a {
color: #172A49 !important;
transition: background-color 200ms linear;
}
.navbar-fixed-top.scrolled li a:hover{
color:#FE5F55 !important;
}
.navbar-fixed-top.scrolled p {
color: #172A49 !important;
transition: background-color 200ms linear;
}
.navbar-fixed-top.scrolled #logo-white {
display: none;
}
.navbar-fixed-top.scrolled #logo-blue {
display: block;
}
.lab-title {
animation: lab-title 4s forwards;
animation-delay: 1s;
opacity: 0;
}
@keyframes lab-title {
0% {
opacity: 0;
}
100% {
opacity: 1;
}
}
div.preload-images {
background: url("/img/stretch-empty.png") no-repeat -9999px -9999px;
background: url("/img/stretch-new-hires3.png" ) no-repeat -9999px -9999px;
}
@keyframes fadein {
0% {background: url("/img/stretch-new-hires3.png" ); background-size: cover; background-repeat: no-repeat;}
100% {background: url("/img/stretch-new-hires3.png"); background-size: cover; background-repeat: no-repeat;}
}
</style>
<!-- Global site tag (gtag.js) - Google Analytics -->
<script async src="https://www.googletagmanager.com/gtag/js?id=UA-130775773-1"></script>
<script>
window.dataLayer = window.dataLayer || [];
function gtag() { dataLayer.push(arguments); }
gtag('js', new Date());
gtag('config', 'UA-130775773-1', {
'linker': {
'accept_incoming': true
}
});
</script>
<script>
$(function () {
$(document).scroll(function () {
var $nav = $(".navbar-fixed-top");
$nav.toggleClass('scrolled', $(this).scrollTop() > $nav.height());
});
});
</script>
</head>
<div class="preload-images"></div>
<body id="top">
<nav class="navbar navbar-fixed-top">
<a class="navbar-brand " href="/">
<p>Mesirov Lab</p>
</a>
<div class="navbar-header">
<button type="button" class="navbar-toggle" data-toggle="collapse" data-target="#myNavbar">
<span class="icon-bar"></span>
<span class="icon-bar"></span>
<span class="icon-bar"></span>
</button>
</div>
<div class="collapse navbar-collapse" id="myNavbar">
<ul class="nav navbar-nav" id="navigation">
<span id="media-space" style="height: 80px"></span>
<li><a href="members/">OUR TEAM</a></li>
<li><a href="pubs/">PUBLICATIONS</a></li>
<li><a href="software/">SOFTWARE/DATA RESOURCES</a></li>
<li><a href="teaching/">TEACHING</a></li>
<li><a href="opportunities/">JOIN US</a></li>
<li><a href="about/">CONTACT</a></li>
</ul>
<a class="navbar-brand navbar-right" href="/" id="ucsd-logo">
<img id="logo-white"src="img/PNG/UCSanDiegoLogo-White.png" width="150px" style="padding:0px; margin:auto;">
<img id="logo-blue" src="img/PNG/UCSanDiegoLogo-BlueGold.png" width="150px" style="padding:0px; margin:auto;">
</a>
</div>
</nav>
<div style="text-align: center; " id="banner">
<div class="container-fluid" style="padding-bottom: 50px;">
<div id="lab-title" class="lab-title">
<h3 style="">
Jill P. Mesirov Lab</h3>
<p style="color: white; font-weight: 100;font-size: 20px; opacity:0;" id="mission-statement">Lorem ipsum dolor sit amet consectetur adipisicing elit.</p>
<div class="row" style="margin:auto; padding-bottom: 100px;" id="banner-btn">
<div class="col-sm-1"></div>
<div class="col-sm-2" style="text-align:center" >
<a class="btn button" href="#about-lab" >
<p style="margin-top: 150px; font-size: 18px;">Learn More</p>
<span class="glyphicon glyphicon-chevron-down" style="font-size: 20px;"></span>
</a>
</div>
<div class="col-sm-2"></div>
<div class="col-sm-2" style="text-align:center">
<a class="btn button" href="#newsfront">
<p style="margin-top: 150px; font-size: 18px;">Featured Publications</p>
<span class="glyphicon glyphicon-chevron-down" style="font-size: 20px"></span>
</a>
</div>
<div class="col-sm-2"></div>
<div class="col-sm-2" style="text-align:center">
<a class="btn button" href="#footer">
<p style="margin-top: 150px; font-size: 18px;">Contact Us</p>
<span class="glyphicon glyphicon-chevron-down" style="font-size: 20px;"></span>
</a>
</div>
<div class="col-sm-1"></div>
</div>
</div>
</div>
</div>
<div style="background-color: white;" id="about-lab">
<div class= "row" style="width: 95%; margin: auto; padding: 50px;">
<div class="col-12 col-sm-3" style="margin: auto; margin-top: 30px; padding:0px;">
<h1 style="margin:auto; padding: 0px; font-size: 25px; margin-bottom: 15px;">Jill P. Mesirov, Ph.D.</h1>
<img src="img/mesirov_portrait.jpg" width="200px" style="">
<p style="font-size: 13px; margin-top: 15px; font-weight: 500;">
UC San Diego, School of Medicine<br>
UC San Diego, Moores Cancer Center
</p>
<p style="font-weight: 100; text-align: left; font-size: 13px; margin-top: 20px;">
<b>Professor of Medicine</b>, Division of Medical Genetics;
<br>
<b>Associate Vice Chancellor</b>
for Computational Health Sciences;
<br>
<b>Co-Lead</b>, Structural and Functional Cancer Genomics Research Program;
<br>
</p>
<a class="btn button" href="members/" style="margin-top: 10px; color:white;">Learn More...</a>
</div>
<div class="col-12 col-sm-8" style="margin: auto; padding: 0px; color: black; margin-top: 30px; text-align: center; margin-left: 70px;">
<p style="text-align: left; margin-bottom: 35px; font-size: 18px;">Research in the Mesirov Lab focuses on cancer genomics applying machine-learning methods to functional data derived from patient tumors. The lab analyzes these molecular data to determine the underlying biological mechanisms of specific
tumor subtypes, to stratify patients according to their relative risks of relapse, and to identify candidate compounds
for new treatments. The overall goal is to treat patients as individuals specific to their tumors. Importantly, the lab
is committed to the development of practical, accessible software tools to bring these methods to the general biomedical
research community. The tools support over 1,000,000 users worldwide.</p>
<div class="col-12 col-md-4" id="front-btn">
<a class="front-icon" href="pubs/" style="font-weight: 600; text-align: center; ">
<img src="img/research-3.png" width="150px">
<p>Computational Biology research</p>
</a>
</div>
<div class="col-12 col-md-4" id="front-btn" >
<a class="front-icon" href="software/" style="font-size: 15px; font-weight: 600; text-align: center;">
<img src="img/soft-4.png" width="150px" style="">
<p>Software and data resources</p>
</a>
</div>
<div class="col-12 col-md-4" id="front-btn" >
<a class="front-icon" href="members/" style="font-size: 20px;font-weight: 600; text-align: center; ">
<img src="img/people-6.png" width="150px">
<p>Meet the lab</p>
</a>
</div>
<div class="col-sm-12">
<a href="#newsfront"
style="font-weight: 400; font-size: 16px; color:#FE5F55;margin: auto;">Recent Featured
Publications<br><span href="#newsfront" class="glyphicon glyphicon-chevron-down"
style="font-size: 20px; margin: 0px; color:#FE5F55"></span></a>
</div>
</div>
</div>
</div>
<div style="background-color: lightgrey" id="newsfront">
<div class="row" style="margin: 0 auto; padding: 25px; padding-top: 100px;">
<div class="container-fluid col-sm-6">
<div class="panel panel-default" style="padding: 0px; margin-top: 20px; box-shadow: 3px 3px 3px grey;">
<h3 class="panel-heading" style="padding: 15px;"> Recent Featured Publications</h3>
<ul class="panel-body" style="padding: 50px; text-align: justify; padding-top: 30px; padding-bottom: 30px;">
<h4><b>2025</b></h4>
<ul>
<li>Garg B, Khan S, Courelli AS, Panneerpandian P, Sheik Pran Babu D, Mose ES, Gulay KCM, Sharma S, Sood D, <b>Wenzel AT</b>, Martsinkovskiy A, Rajbhandari N, Patel J, Jaquish D, Esparza E, Jaque K, Aggarwal N, Lambies G, D'Ippolito A, Austgen K, Johnston B, Orlando DA, Jang GH, Gallinger S, Goodfellow E, Brodt P, Commisso C, Tamayo P, <b>Mesirov JP</b>, Tiriac H, Lowy AM. MICAL2 Promotes Pancreatic Cancer Growth and Metastasis. Cancer Res. 2025 Jan 2. doi: 10.1158/0008-5472.CAN-24-0744. Epub ahead of print. <a href="https://pubmed.ncbi.nlm.nih.gov/39745352/" target="_blank">PMID: 39745352</a>.</li>
</ul>
<h4><b>2024</b></h4>
<ul>
<li>Klemm JD, Singer DS, <b>Mesirov JP</b>. Transforming Cancer Research through Informatics. Cancer Discov. 2024 Oct 4;14(10):1779-1782. doi: 10.1158/2159-8290.CD-24-0604. <a href="https://pubmed.ncbi.nlm.nih.gov/39363746/" target="_blank">PMID: 39363746</a>; PMCID: PMC11463720.</li>
</ul>
<h4><b>2023</b></h4>
<ul>
<li><b>Chapman OS</b>, Luebeck J, <b>Sridhar S</b>, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, <b>Pagadala MS</b>, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, Adam M, Morgan L, Wani S, Tiwari A, Guccione C, Lin Y, Dutta A, Lo YY, <b>Juarez E</b>, <b>Robinson JT</b>, Korshunov A, Michaels JA, Cho YJ, Malicki DM, Coufal NG, Levy ML, Hobbs C, Scheuermann RH, Crawford JR, Pomeroy SL, Rich JN, Zhang X, Chang HY, Dixon JR, Bagchi A, Deshpande AJ, Carter H, Fraenkel E, Mischel PS, Wechsler-Reya RJ, Bafna V, <b>Mesirov JP</b>, Chavez L. Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nat Genet. 2023 Dec;55(12):2189-2199. doi: 10.1038/s41588-023-01551-3. Epub 2023 Nov 9. <a href="https://pubmed.ncbi.nlm.nih.gov/37945900/" target="_blank">PMID: 37945900</a>; PMCID: PMC10703696.</li>
<li>Castanza AS, Recla JM, Eby D, Thorvaldsdóttir H, Bult CJ, Mesirov JP. Extending support for mouse data in the Molecular Signatures Database (MSigDB). Nat Methods. 2023 Nov;20(11):1619-1620. doi: 10.1038/s41592-023-02014-7. <a href="https://pubmed.ncbi.nlm.nih.gov/37704782/" target="_blank">PMID: 37704782</a>; PMCID: PMC11397807.</li>
<li>Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, <b>Wenzel AT</b>, Song MJ, <b>Pagadala MS</b>, <b>Clubb LM</b>, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, <b>Mesirov JP</b>, Gutkind JS. The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nat Immunol. 2023 Aug;24(8):1318-1330. doi: 10.1038/s41590-023-01529-7. Epub 2023 Jun 12. <a href="https://pubmed.ncbi.nlm.nih.gov/37308665/" target="_blank">PMID: 37308665</a>; PMCID: PMC10735169.</li>
<li><b>Robinson JT</b>, <b>Thorvaldsdottir H</b>, Turner D, <b>Mesirov JP</b>. igv.js: an embeddable JavaScript implementation of the Integrative Genomics Viewer (IGV). Bioinformatics. 2023 Jan 1;39(1):btac830. doi: 10.1093/bioinformatics/btac830. <a href="https://pubmed.ncbi.nlm.nih.gov/36562559/" target="_blank">PMID: 36562559</a>; PMCID: PMC9825295.</li>
</ul>
<a class="btn button" href="pubs/" style="margin-top: 10px; color:white;">All Publications</a>
</ul>
</div>
</div>
<div class="container-fluid col-sm-6">
<!--
<div class="panel panel-default" style="padding: 0px; margin:0 auto; margin-top: 20px; box-shadow: 3px 3px 3px grey;">
<h3 class="panel-heading" style="padding: 15px;">Open Positions</h3>
<ul class="panel-body" style="padding:30px; margin: 0 auto;">
<li>
<h4>Bioinformatics Scientist</h4>
<p>The Mesirov Lab at UC San Diego seeks an exceptional candidate who is passionate about accelerating the pace of cancer research through the analysis of genomic data and making sophisticated computational methods available to the research community at large through advanced, accessible software tools.</p>
</li>
<a class="btn button" href="opportunities/" style="margin-top: 10px; color:white;">Learn More...</a>
</ul>
</div>
-->
<div class="panel panel-default" style="padding: 0px; margin-top: 20px; box-shadow: 3px 3px 3px grey;">
<h3 class="panel-heading" style="padding: 15px;">Upcoming events</h3>
<ul class="panel-body" style="padding: 50px; text-align: justify; padding-top: 30px; padding-bottom: 30px;">
<a class="btn button" href="teaching/" style="margin-top: 10px; color:white;">Courses & Workshops</a>
</ul>
</div>
</div>
</div>
<!-- <a href="#top" style="text-align:center; ">
<div style="margin:auto; margin-top: 10px; background: rgba(0,0,0,0.8); width:100%; padding:20px;">
<div class="glyphicon glyphicon-chevron-up" style="font-size: 20px; color: white;"></div>
<br>
</div>
</a> -->
</div>
<footer style="margin-top: 0px; padding: 50px; padding-bottom: 80px;" id='footer'>
<div class="row">
<div class="col-sm-3" style="padding-top:0px; ">
<h1 style="margin-top:0px;">Mesirov Lab</h1>
<p>
Department of Medicine<br>
UC San Diego, School of Medicine<br>
Floor 2A, Biomedical Research Facility II<br>
La Jolla, CA 92093<br><br>
Mail Code: 0602<br>
</p>
<!-- <p style="font-size: 10px;">© Copyright Mesirov Lab 2018 </p> -->
</div>
<div class="col-sm-4">
</div>
<div class="col-sm-5 row">
<div class="col-sm-4">
<a href="members/">Our Team</a><br><br>
<a href="projects/">Research</a>
</div>
<div class="col-sm-4">
<a href="pubs/">Publications</a><br><br>
<a href="software/">Software</a>
</div>
<div class="col-sm-4">
<a href="teaching/">Teaching</a><br><br>
<a href="about/">Contact</a><br><br>
<a href="opportunities/">Join Us</a>
</div>
<div class="col-12" style="text-align: right;">
</div>
</div>
</div>
</footer>
<script src="js/smooth-scroll.js"></script>
<script src="https://ajax.googleapis.com/ajax/libs/jquery/3.3.1/jquery.min.js"></script>
<script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.4.0/js/bootstrap.min.js"></script>
</body>
</html>