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education/HADDOCK24/index.md

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---
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layout: page
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title: "HADDOCK Tutorials for version 2.4"
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title: "HADDOCK2.4 tutorials"
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tags: [MODELLER, GROMACS, HADDOCK, molecular dynamics, homology modelling, docking, p53, MDM2]
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image:
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feature: pages/banner_education-thin.jpg
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---
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In this page you can find links to tutorials on the usage of our software and webportal [HADDOCK 2.4](https://wenmr.science.uu.nl/haddock2.4/){:target="_blank"}.
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In this page you can find links to tutorials on the usage of our web server [HADDOCK 2.4](https://wenmr.science.uu.nl/haddock2.4/){:target="_blank"} and command-line tool installation tutorial.
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* table of contents
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{:toc}
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<hr>
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# Getting started with HADDOCK web server
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* [**Basic docking run with HADDOCK web server**](/education/HADDOCK24/HADDOCK24-protein-protein-basic):
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A tutorial demonstrating a step-by-step use of the HADDOCK web server to model a protein-protein complex using interface information derived from NMR chemical shift perturbation data.
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This tutorial does not require any Linux expertise and only makes use of our web server and [PyMol](https://www.pymol.org){:target="_blank"} for visualisation/analysis.
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# Basic web tutorials
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# Basic web server tutorials
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* [**HADDOCK2.4 basic antibody-antigen docking tutorial**](/education/HADDOCK24/HADDOCK24-antibody-antigen-basic):
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This tutorial demonstrates the use of HADDOCK2.4 for predicting the structure of an antibody-antigen complex using information
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* [**HADDOCK2.4 basic protein-glycan tutorial**](/education/HADDOCK24/HADDOCK24-protein-glycan):
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This tutorial explains the modelling of protein-glycan complexes using the HADDOCK2.4 webserver and [PyMol](https://www.pymol.org){:target="_blank"} for visualisation/analysis. It is a basic, fully web-based tutorial requiring no Linux expertise.
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# Intermediate web tutorials
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# Intermediate web server tutorials
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* [**HADDOCK2.4 basic Protein-DNA tutorial**](/education/HADDOCK24/HADDOCK24-protein-DNA-basic):
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This tutorial demonstrates the use of HADDOCK2.4 for predicting the structure of a protein-DNA complex in which two protein units bind to the DNA in a symmetrical manner (3CRO). Next to ambiguous restraints to drive the docking symmetry restraints are defined to enforce symmetrical protein binding.
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The tutorial does not require any Linux expertise and only makes use of the DISVIS and HADDOCK web servers and [PyMol](https://www.pymol.org){:target="_blank"} for visualisation/analysis.
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It now also includes a part describing the modelling of these homomeric complexes using AlphaFold2.
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# Intermediate command-line tutorials
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* [**HADDOCK2.4 local installation tutorial**](/education/HADDOCK24/HADDOCK24-local-tutorial):
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A tutorial demonstrating the installation and use of a local installation of HADDOCK2.4. It demonstrates various docking scenarios.
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You will need for this a valid license of HADDOCK2.4.
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# Advanced tutorials (mix of web server and command-line)
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# Advanced web server tutorials
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* [**HADDOCK2.4 ab-initio, multi-body symmetrical docking tutorial**](/education/HADDOCK24/HADDOCK24-CASP-CAPRI-T70):
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A tutorial demonstrating multi-body docking with HADDOCK using its ab-initio mode with symmetry restraints.
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This tutorial demonstrates the use of LightDock for predicting the structure of membrane receptor–soluble protein complex using the topological information
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provided by the membrane to guide the modelling process. The resulting LightDock models are then refined using HADDOCK.
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# Documentations
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# Documentation
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* [**HADDOCK best practice guide**](https://www.bonvinlab.org/software/bpg/){:target="_blank"}
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* [**HADDOCK restraints generation**](https://www.bonvinlab.org/haddock-restraints/home.html){:target="_blank"}:
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A guide for the `haddock-restraints` tool allowing to generate various types of distance restraints for use in HADDOCK, also available via [a graphical user interface](http://wenmr.science.uu.nl/new/haddock-restraints){:target="_blank"}.
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A guide for the `haddock-restraints` tool allowing to generate various types of distance restraints for use in HADDOCK, also available via [a graphical user interface](http://wenmr.science.uu.nl/new/haddock-restraints){:target="_blank"}.
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# HADDOCK2.4 local installation tutorial
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* [**HADDOCK2.4 local installation tutorial**](/education/HADDOCK24/HADDOCK24-local-tutorial):
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A tutorial demonstrating the installation and use of a local installation of HADDOCK2.4. It demonstrates various docking scenarios.
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You will need for this a valid license of HADDOCK2.4.

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