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Damiano Piovesan edited this page Jan 22, 2024 · 32 revisions

Workflow

/doc/figures/workflow_bg.png

Ontology and topological sorting

  • Ground truth and predictions
  • Information accretion

Evaluation

Parameters

Argument Default value Description
-out_dir “results” Output directory (tsv files + log). Either relative to current path or absolute
-ia Information accretion file
-no_orphans False (flag) Exclude orphans nodes (e.g. roots) from the calculation
-norm “cafa” Normalization strategy CAFA strategy (cafa) Consider predicted targets (pred) Consider ground truth proteins (gt)
-prop “max” Ancestor propagation strategy Propagate the max score of the traversed subgraph iteratively (max) Propagate with max until a different score is found (fill)
-th_step 0.01 Threshold step size in the range [0, 1). A smaller step, means more calculation
-max_terms Number of terms for protein and namespace to consider in the evaluation
-threads 4 Parallel threads. 0 means use all available CPU threads. Do not use multi thread if you are short in memory
  • Normalization
  • Roots
  • Score propagation
  • Thresholds granularity
  • Monotonic curves
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